A few fringe sites (yeah, I know someone will take offence at that, but really it's true) use an email filter system called "Waitlisting". The idea is that if you are a new sender, instead of delivering your email the system will send you back a notice that you've been waitlisted and ask you to go through a web verification process. Sometimes that's as simple as clicking a link, sometimes not. Until you do that your message will not be delivered.
Sounds like a great way to combat spam, right?
Until you're on the sending end. Here's a for-instance. I get hundreds of emails a day. I received a tech support email from someone about a free Android application that I wrote. I replied. I get "waitlisted."
I'd rather spend 5 minutes writing this blog post than go through his waitlisting policies to prove I'm really the guy that he already emailed.
As a system administrator it probably frustrates me more than others because I know there are other systems such as greylisting that are just as effective at reducing spam and don't inconvenience every person you want to communicate with.

